{"id":444,"date":"2008-05-21T08:43:13","date_gmt":"2008-05-21T07:43:13","guid":{"rendered":"http:\/\/www.deinayurveda.net\/wordpress\/?p=444"},"modified":"2010-02-08T15:24:04","modified_gmt":"2010-02-08T14:24:04","slug":"jiaogulan-%e2%80%93-das-kraut-der-unsterblichkeit","status":"publish","type":"post","link":"http:\/\/www.deinayurveda.net\/wordpress\/2008\/05\/jiaogulan-%e2%80%93-das-kraut-der-unsterblichkeit\/","title":{"rendered":"Jiaogulan \u2013 das Kraut der Unsterblichkeit"},"content":{"rendered":"<p style=\"text-align: center;\"><span style=\"color: #008000;\"><strong><a title=\"jio.jpg\" href=\"http:\/\/www.deinayurveda.net\/wordpress\/wp-content\/uploads\/2008\/05\/jio.jpg\" rel=\"shadowbox[sbpost-444];player=img;\"><\/a><a title=\"jio.jpg\" href=\"http:\/\/www.deinayurveda.net\/wordpress\/wp-content\/uploads\/2008\/05\/jio.jpg\" rel=\"shadowbox[sbpost-444];player=img;\"><img src=\"http:\/\/www.deinayurveda.net\/wordpress\/wp-content\/uploads\/2008\/05\/jio.thumbnail.jpg\" alt=\"jio.jpg\" \/><\/a> <\/strong><\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"color: #008000;\"><strong>Eine Gingseng Alternative<\/strong><\/span> <span style=\"color: #008000;\"><strong>aus der chinesischen Volksmedizin<\/strong><\/span><\/p>\n<p align=\"justify\">Ist jetzt sogar schon als kleine Pflanze im Blumenhandel erh&#228;ltlich, <em>(siehe nachstehende Bezugsquellen)<\/em> man kann annehmen, dass man in Zukunft noch viel &#252;ber dieses faszinierende Kraut h&#246;ren wird. Anbei finden Sie eine ausf&#252;hrliche Information\u00a0des Lieferanten von Frau Dr. Doris Ehrenberger &#8211; <em>Gesellschaft f. holistische Medizin<\/em>, der einen qualitativ einzigartigen Extrakt herstellt und auch eine wissenschaftliche Dokumentation dazu f&#252;hrt.<\/p>\n<p align=\"justify\">Seit 3 Wochen gedeiht jiogulan zum ersten Mal auch in meinem Biogarten und w&#228;chst problemlos. An einer warmen Hausmauer (die Nachts die W&#228;rme speichert) mit einer Bambusrankstange scheint sich die Pflanze bislang sehr wohl zu f&#252;hlen. Die &#220;berwinterung jiaogulans und meine Erfahrungen erg&#228;nze ich kommendes Fr&#252;hjahr in diesem Beitrag.<\/p>\n<p align=\"justify\">Jiaogulan wurde bereits 1400 nach Chr. in alten chinesischen Schriften erw&#228;hnt und z&#228;hlt zu den traditionellen Pflanzen der chinesischen Medizin. Es ist viermal so reich an Gypenosiden als Ginseng. In der Region Guizhou wird das Kraut t&#228;glich als Tee getrunken und soll zur hohen Zahl an &#252;ber 100 J&#228;hrigen enorm beitragen. Kein Wunder, denn Jiaogulan unterst&#252;tzt gegen alle Herz\/Kreislaufrisikofaktoren!<\/p>\n<p><span style=\"color: #008000;\">Jiaogulan wirkt:<\/span><\/p>\n<ul>\n<li>Stressmindernd &#8211; beruhigend auf strapazierte Nerven ohne m&#252;de zu machen<\/li>\n<li>Nerven st&#228;rkend, anregend und reaktionsf&#246;rdernd (Sport, Arbeit, Schule)<\/li>\n<li>Verk&#252;rzt Regenerationszeit nach Anstrengung<\/li>\n<li>Senkt Blutfette und Blutzucker<\/li>\n<li>Senkt Cholesterin und Triglyceride<\/li>\n<li>Unterst&#252;tzt Fettstoffwechsel und Gewichtsabnahme<\/li>\n<li>Reguliert den Blutdruck &#8211; senkt zu hohen und hebt zu niedrigen Blutdruck<\/li>\n<li>Beugt Thrombose-, Schlaganfall- und Herzinfarktrisiko vor<\/li>\n<li>St&#228;rkt das Herz, die Pumpleistung und die allgemeine Durchblutung<\/li>\n<li>Verbessert und unterst&#252;tzt die Leber<\/li>\n<li>St&#228;rkt das Immunsystem (die Lymphozyten)<\/li>\n<li>F&#246;rdert die Bildung der wei&#223;en Blutk&#246;rperchen (nach Chemo oder Bestrahlung!)<\/li>\n<li>Wirkt antioxidativ und tumorhemmend durch das Glycosid Ginsenosid RhL<\/li>\n<\/ul>\n<p align=\"justify\">Die auch bei uns leicht zu ziehende Gynostemma pentaphyllum ist eine Rankpflanze aus der Familie der K&#252;rbisgew&#228;chse. Man kann sie im Gartenbeet oder im Topf kultivieren. Jiaogulan kann bis zu zwei Meter hoch werden und ben&#246;tigt ein Kletterger&#252;st. Peter Fischer-Colbrie, Pr&#228;sident der &#214;sterreichischen Gartenbaugesellschaft, empfiehlt einen halbschattigen Standort. Bei &#220;berwinterung im Freiland sterben die oberirdischen Teile ab, im Fr&#252;hjahr sollte ein neuer Austrieb erfolgen.<\/p>\n<p align=\"justify\">Im Topf kann die Pflanze an einem hellen Fenster im Zimmer &#252;berwintern, als ideal hat sich daf&#252;r ein Fensterbrett nach S&#252;den ohne darunter liegenden Heizk&#246;rper erwiesen. Vor trockener Heizungsluft ist sie durch ausreichendes Gie&#223;en und Bespr&#252;hen zu sch&#252;tzten.<\/p>\n<p align=\"justify\">Als Substrat f&#252;r die Topfkultur eignet sich gute K&#252;belpflanzenerde. W&#228;hrend der Vegetationsperiode sollte w&#246;chentlich, im Winter alle drei Wochen und im Fr&#252;hjahr alle zwei Wochen mit handels&#252;blichem Fl&#252;ssign&#228;hrstoff ged&#252;ngt werden.<\/p>\n<p align=\"justify\">Jiaogulan kann leicht mittels Stecklingen in einem n&#228;hrstoffarmen Substrat (Aussaaterde und Quarzerde 1:1 gemischt) in einem Minigew&#228;chshaus vermehrt werden. Auch in Wasser bewurzelte Triebe wachsen in dieser Erde gut an.<\/p>\n<p align=\"justify\">Anwendung mittels kauen der Bl&#228;tter und Tee.<\/p>\n<p align=\"left\"><strong><em><span style=\"color: #008000;\">Kontakte &#8211; Jiaogulan Pflanze:<\/span><\/em><\/strong><br \/>\n<em><span style=\"color: #808080;\">\u2022 &#214;sterreichische Gartenbau Gesellschaft, <\/span><\/em><em><span style=\"color: #808080;\">Pr&#228;sident DI Dr. Peter Fischer-Colbrie<\/span><\/em><em><span style=\"color: #808080;\"> Siebeckstra&#223;e 14, 1220 Wien, Tel: 01\u00a0&#8211;\u00a0512\u00a084\u00a016, E-Mail: oegg@oegg.or.at, www.garten.or.at<br \/>\n\u2022 G&#228;rtnerei Gerhard Krepela, 1140 Wien, Tel: 01\u00a0&#8211;\u00a0914\u00a043\u00a016, www.krepela.at<br \/>\n\u2022 G&#228;rtnerei Johannes K&#228;fer, 3264 Gresten\/N&#214;, Tel: 07487\u00a0&#8211;\u00a02358, www.blumenkaefer.at<br \/>\n\u2022 G&#228;rtnerei Starkl, vier Mal in Wien und Nieder&#246;sterreich, Tel: 07476\u00a0&#8211;\u00a076565 , www.starkl.at<\/span><\/em><\/p>\n<p align=\"justify\">\n<p align=\"center\"><span style=\"color: #008000;\">JiaogulanExTM<br \/>\nGynostemma Pentaphyllum Extract<br \/>\nThe Ginseng Alternative that offers superior Health Benefits<\/span><br \/>\nTable of Contents<\/p>\n<p>1. Overview<br \/>\n2. Summary of Clinical Evaluation<br \/>\n3. Toxicity Data<br \/>\n4. Proprietary Strain and Extraction Process<br \/>\n5. Specification<br \/>\n6. Indications, Contraindications, Adverse Effects and Drug Interactions<br \/>\n1. Overview<\/p>\n<p>Background<\/p>\n<p>Jiaogulan is a member of the gourd family that grows in southern China and some neighboring countries. 16 species and 3 variations of Jiaogulan have been discovered and documented so far. Jiaogulan has been used in China for over a thousand years to help relieve\/ease coughs, phlegm, chronic bronchitis, and toxic and virus conditions.<\/p>\n<p>In 1976, Japanese scientists first isolated the key ingredients<br \/>\nin Jiaogulan, the gypenosides. 82 gypenosides have been identified by Chinese scientists thus far, 4 of them have the exact same chemical structures as the ginsenosides Rb1, Rb3, Rd, and F2 in ginseng (1, 2, 3 and 4).<\/p>\n<p>Jiaogulan is relatively new to the list of adaptogens. According to recent studies, it contains nearly four times as many saponins as Panax ginseng. These saponins, known as gypenosides, are similar to the ginsenosides and panaxosides found in Asian ginseng. Preliminary studies also suggest Jiaogulan may have even more powerful regulatory effects on a number of body systems than does Asian ginseng. In addition, Jiaogulan has demonstrated antibacterial and anti-inflammatory properties and a beneficial effect on blood pressure regulation. Jiaogulan also has been shown to bolster the immune system, improve fat metabolism, moderate cholesterol levels, and enhance strength and physical endurance.<\/p>\n<p>Summary of Health Benefits<\/p>\n<p>Jiaogulan has been scientifically studied and clinically shown to:<\/p>\n<p>1. Moderate cholesterol levels<br \/>\n2. Improve fat metabolism<br \/>\n3. Beneficial effects on blood pressure regulation<br \/>\n4. Promote and support immune functions<br \/>\n5. Promote and support liver functions<br \/>\n6. Promote longevity.<\/p>\n<p>Active ingredients<\/p>\n<p>Chemical analysis has shown that Jiaogulan contains (1, 2, 3, 4 and 5):<\/p>\n<p>\uf06c Gypenosides<br \/>\n\uf06c Significant amounts of trace iron, calcium, copper, selenium, etc.<br \/>\n\uf06c Amino acids<br \/>\n\uf06c Vitamins B, C &amp; E<br \/>\n\uf06c Flavones<\/p>\n<p>Reference<\/p>\n<p>1. Guo X.L., et al. Studies on the chemical constituents of Gynostemma longipes. Beijing Medical<br \/>\nUniversity, Beijing, China. Journal of Pharmacology 1997 Jul; 32(7):524-9.<br \/>\n2. He W., et al. Dynamic features of some biochemical constituents in Gynostemma pentaphyllum<br \/>\nunder different environments. Chinese Academy of Sciences. Journal of Applied Environmental<br \/>\nScience, 2000 Feb; 11(1):149-51.<br \/>\n3. Cui J., et al. Gynostemma pentaphyllum: identification of major sapogenins and differentiation<br \/>\nfrom Panax species. Clinical Research Centre, Huddinge University Hospital, Karolinska Institute,<br \/>\nSE-141 86, Huddinge, Sweden. Eur J Pharm Sci 1999 Jul; 8(3):187-91.<br \/>\n4. Hu L., et al. New triterpenoid saponins from Gynostemma pentaphyllum. Shanghai Institute of Materia<br \/>\nMedica, Academia Sinica, Shanghai, China. J Nat Prod 1996 Dec; 59(12):1143-5.<br \/>\n5. Paicente S., et al. New dammarane-type glycosides from Gynostemma pentaphyllum. Dipartimento di<br \/>\nChimica della Sostanze Naturali, Universita degli Studi di Napoli, Federico II, Italy. J Nat Prod 1995<br \/>\nApr; 58(4):512-9.<\/p>\n<p>2. Summary of Clinical Evaluation<\/p>\n<p>Enhances Cardiovascular Functions and Nitric Oxide Production<\/p>\n<p>Jiaogulan has demonstrated in human clinical studies (1, 2, 3, 4 and 5) to have positive effect on raising the HDL cholesterol and lowering the LDL cholesterol. These effects are possibly due to Jiaogulan&#8217;s ability to reduce the decomposition of lipids in adipose cells caused by ACTH, to prevent the synthesis of glucose to lipids within adipose cells and to prevent fat deposits on blood vessel walls. Other clinical studies (6, 7) have reported Jiaogulan&#8217;s positive effects on hypertension and atherosclerosis. Several animal based studies (8, 9 and 10) indicate a possible link between Jiaogulan and a decrease in the occurrence of circulatory and cardiovascular incidences. In vitro study by Vanderbilt University Medical Center on G. Pentaphyllum extracts (11) reveals Jiaogulan&#8217;s effect on increasing nitric oxide production. Mounting scientific evidence indicates that increases in nitric oxide level help promote cardio-vascular health.<br \/>\nThe protective effects of gypenoside (GPS) against damages induced by exogenous oxygen free radicals (OFR) on the basilar artery of rabbits were studied. Exogenous OFR were generated by the electrolysis of Krebs solution. The perfusion pressure and malonyldialdehyde (MDA) content in the basilar artery were increased; release of Endothelium-derived relaxing factor (EDRF), nitrite content and SOD activity in basilar artery decreased after OFR damage, GPS 25, 50, 100ug\/mL pretreatment exhibited a concentration dependent decrease in constriction response of the basilar artery. Results also showed that GPS 100ug\/mL reversed the rise of MDA and the reduction of SOD activity, nitrite and EDRF release.<\/p>\n<p>Promote and Support Immune Functions<\/p>\n<p>Jiaogulan has shown in in vitro and in vivo studies (12, 13, 14, 13, 14, 15, 16, 17, 18 and 19) to support and promote immune functions. The effects of Jiaogulan on human rectal adenocarcinoma cell line (Hce8693) and human fetal lung diploid fibroblast cell strain (4BS, as normal control) were investigated in vitro. Hce 8693 cells were inhibited by the extract in certain concentrations and for certain times, which were dose-related, such as decreasing DNA synthesis and the cleavage indexes, cellular degeneration and necrosis. One of Jiaogulan&#8217;s antineoplastic mechanisms is probably due to the inhibition of proliferation as well as the direct cytotoxicity to abnormal cells.<\/p>\n<p>Promote and Support Liver Functions<\/p>\n<p>Jiaogulan has shown in in vitro studies to support and promote normal liver functions. One in vitro (20) study demonstrated that gypenosides in Jiaogulan can induce apoptosis in human hepatoma cells. Another in vitro study (21) demonstrated that gypenosides in Jiaogulan has the potential to provide hepatoprotective and antifibrotic protection on chronic liver injury induced by CCl4 for 8 wks. Still another in vitro study (22) has showed that gypenosides in Jiaogulan exerts anti-inflammatory activity and hepatoprotective activity against CC14-induced liver damage.<\/p>\n<p>Promote Longevity<\/p>\n<p>In vitro study has shown that during the cell proliferation period, Jiaogulan can promote proliferation of skin cells. Cells are the foundation of life. Jiaogulan can serve as the activator of cells, accelerate the reproductive capacity in cells, and prolong cell life. Fatigue tests have been done on mice, and Jiaogulan has been shown to prolong the swimming period of mice until death due to fatigue (23). Immunity tests have also been done proving that Jiaogulan can increase immunity in body fluid and cells (24).<\/p>\n<p>References<\/p>\n<p>1. Shi J., et al. Effects of Jiaogulan on patients with hyperlipidemia. Journal of Norman Bethune University of Medical Science, 2001; vol.1, No.4, p343.<br \/>\n2. Lin C., et al. Safety and Efficacy of Jiaogulan on regulating lipoprotein. Journal of Guangdong Medical College 2001 Vol.19 No.3:.200-201.<br \/>\n3. Kang J., et al. Effects of Jiaogulan in Blood Lipid Metabolism. Chinese Traditional and Herbal Drugs 2000; 31 (10): 770-771.<br \/>\n4. Kimura, Y. et al. Effects of crude saponins of Gynostemma pentaphyllum on lipid metabolism. Shoyakugaku Zasshi. Japanese. 1983; 37(3): 272-275.<br \/>\n5. Yu, C. Therapeutic effect of a gypenosides tablet on 32 patients with hyperlipaemia. Journal of the integrated medicine of western and traditional Chinese medicines, HuBei State, China. 1993. 15(3): 21.<br \/>\n6. Wang J., et al. Therapeutic observation of Jiaogulan&#8217;s effects on Angina Pectoris caused by atherosclerosis. China Traditional and Western Medicine ER Magazine 1999 Vol. 2 (6).<br \/>\n7. Lu, G.H., et al. Comparative study of anti-hypertensive effect of Gypenosides, Ginseng and Indapamide in patients with essential hypertension. Guizhou Medical Journal. 1996; 20:1.<br \/>\n8. Tan, H., et al. Antithrombotic effect of Gynostemma pentaphyllum. Integrated Medicine Journal of China. 993 May; 13(5): 278-280, 261.<br \/>\n9. Wu, J., et al. Effects of gypenosides on platelet aggregation and camp levels in rabbits. Pharmacology and Toxicology Journal of China. 1990; 4(1): 54-57.<br \/>\n10. Chen, L.F., et al. Comparison between the effects of gypenosides and gypenosides on cardiac function and hemodynamics in dogs. Pharmacology and Toxicology Journal of China. 1990; 4(1): 17-20.<br \/>\n11, Tanner M.A., et al. The direct release of nitric oxide by gypenosides derived from the herb<br \/>\nGynostemma pentaphyllum. Division of Cardiology, Vanderbilt University Medical Center and the<br \/>\nDepartment of Veterans Affairs Hospital, Nashville, Tennessee, USA. Nitric Oxide 1999<br \/>\nOct; 3(5):359.<br \/>\n12. Wang Q.F., et al. Regulation of Bcl-2 family molecules and activation of caspase cascade involved<br \/>\nIn gypenosides-induced apoptosis in human hepatoma cells. China Medical College, Taichung, Taiwan. Cancer Letter 2002 Sep 26; 183(2):169-78.<br \/>\n13. Zhou Z, et al. Experimental study on the influence of Gynostemma pentaphyllum Mak. upon point<br \/>\nmutation of Ha-ras oncogene in blocking leukoplakia from canceration. Shanghai Second Medical<br \/>\nUniversity, Shanghai 200011, China. China pharmacology journal 2000 Mar; 35(2):91-4.<br \/>\n14. Zhu S., et al. Inhibitory effects of gynostemma pentaphyllum on the UV induction of<br \/>\nbacteriophage lambda in lysogenic Escherichia coli. College of Life Sciences, Wuhan University,<br \/>\nWuhan, China. Current Microbiol 2001 Oct; 43(4):299-301.<br \/>\n15. Zhou Z., et al. Effect of gynostemma pentaphyllum mak. on carcinomatous conversions of golden<br \/>\nhamster cheek pouches induced by dimethylbenzanthracene: a histological study. Shanghai<br \/>\nSecond Medical University, Shanghai, China. Chin Med J (Engl) 1998 Sep; 111(9):847-50.<br \/>\n16. Chen W.C., et al. Protective effects of Gynostemma pentaphyllum in gamma-irradiated mice.<br \/>\nNational Tsing-Hua University, Hsinchu, Taiwan. Am J Chin Med 1996; 24(1):83-92.<br \/>\n17. Wang C., et al. A preliminary observation of preventive and blocking effect of Gynostemma<br \/>\npentaphyllum (Thunb) Makino on esophageal cancer in rats. Hua Xi Yi Ke Da Xue Xue Bao 995<br \/>\nDec; 26(4):430-2.<br \/>\n18. Han M.Q., etc. Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle<br \/>\nof human lung Aden carcinoma cell. Longhead Hospital, Shanghai University of TCM. Shogun<br \/>\nHong Xi Yi Jive He Zap Zhan 1995 Mar; 15(3):147-9.<br \/>\n19. Zhang H., etc. Protoplast culture and plant regeneration from the suspension cells of<br \/>\nGynostemma pentaphyllum (Thumb) Mak. Cytogenetics Institute, Nanjing Agricultural University,<br \/>\nChina. Chin J Biotechnol 1995; 11(3):207-11.<br \/>\n20. Chen J.C., et al. Therapeutic effect of gypenoside on chronic liver injury and fibrosis induced by<br \/>\nCCl4 in rats. Chinese Medical College, Taichung, Taiwan. Am J Chin Med 2000; 28(2):175-85.<br \/>\n21. Lin C.C., et al. Antioxidant and hepatoprotective effects of Anoectochilus formosanus and<br \/>\nGynostemma pentaphyllum. Kaohsiung Medical College, Kaohsuing, Taiwan. Am J Chin Med<br \/>\n2000; 28(1):87-96.<br \/>\n22. Chen J.C., et al. Gypenoside induces apoptosis in human Hep3B and HA22T tumour cells. China<br \/>\nMedical College, Taiwan. Cytobios 1999; 100(393):37-48.<br \/>\n23. Zhou, S.R. A Preliminary study on the effects of Gynostemma pentaphyllum on endurance,<br \/>\nspontaneous motor activity and superoxide dismutase in mice. Asia Pacific Journal of<br \/>\nPharmacology 1990; 5(4): 321-322.<br \/>\n24. Arichi, S., et al. Saponins of Gynostemma pentaphyllum as tonics. Kakai Tokyo Koho.<br \/>\nJpn. 1985. 60(105): 626.<br \/>\n3. Toxicity Data<br \/>\nAcute Toxicology Tests (LD50)<\/p>\n<p>Oral LD50 for mice: 4.5g\/kg and I.P. LD50 for mice: 2826mg\/Kg of Jiaogulan extract (*) (1). Peritoneal injection: 0.768g\/Kg for mice and 1.85g\/Kg for rats. Oral LD50: 48.94g\/Kg (3).<\/p>\n<p>Sub-acute, Sub-chronic Tests<\/p>\n<p>Rats were orally administered 8g\/kg of Jiaogulan extract (*) for 4 weeks. No abnormality was found in the heart, lung, liver, kidney, testicles and ovary of the rats. WBC, RBC, liver and kidney function of the rats were also found to be normal (1).<\/p>\n<p>Large white mice were administered 1\/5, 1\/10, 1\/20 of LD50 dosage for 4 weeks and 1\/10, 1\/20 of LD50 dosage for 90 days. No adverse effects were found in the heart, lung, liver, kidney, testicles, ovary, WBC, RBC, liver and kidney function of the mice (3).<\/p>\n<p>Accumulative Toxicity Test<\/p>\n<p>Rats were orally administered 4g\/kg of Jiaogulan extract (*) for 3 months. No abnormality was found in the heart, liver, kidney, testicles and ovary of the rats. WBC, RBC, ECG, liver and kidney function of the rats were also found to be normal (1).<\/p>\n<p>Carcinogen, Mutation\/Deformity Tests<\/p>\n<p>Mice were randomly divided into 3 groups and orally administered 1000mg\/kg, 2500mg\/kg and 5000mg\/kg of Jiaogulan extract (*) for the first, second and third groups for 11 days. The micronucleus rates of PEC in mice bone marrow induced by cyclophosphamide were 11.9\u2030 (for the 1000mg\/kg group), 8.5\u2030 (for the 2500mg\/kg group) and 13.6\u2030 (for the 5000mg\/kg group) compared to 29.9\u2030 for the none-treatment (cyclophosphamide) group at P&lt;0.05 (2).<\/p>\n<p>* Jiaogulan extract (80% gypenosides) in mg dissolved in distilled water.<br \/>\nReference<br \/>\n1. Minxia Zheng. Research and view on Jiaogulan. Zhejiang Journal of Integrated Traditional and Western Medicine. 1996, 6(1): 54-55.<br \/>\n2. Yangyang Du, Ziyao Mo. Study on the mutagenic and antimutagenic potentials of Gypenosides in Mice. Carcinogenesis Teratogenesis and Mutagenesis (in Chinese), 1995, 7(3): 160-163.<br \/>\n3. Yang, G., et al. Acute and long-term toxicological studies on gypenosides-containing tonics. Guiyang Medical College Publication 1993 18(4):264.<br \/>\n4. Proprietary Strain and Extraction Process<\/p>\n<p>The extraction process is started with the freshest premium Jiaogulan plant from the region in China that is known to contain the richest full spectrum nutrients compared to all species and variations of Jiaogulan grown in China. Then they are processed with our proprietary PureExtractTM process which uses no filler or binding materials. This unique combination allows to produce the highest purity standardized full spectrum extract, JiaogulanExTM. JiaogulanExTM power and extracts (from 30% to 98% Gypenosides) are guaranteed to exceed our or customers&#8216; specifications, as confirmed by in-house and third-party laboratory analysis (HPLC and other accepted testing methods).<\/p>\n<p>Reference<\/p>\n<p>1. Xiao X.H., etc. Systematic concept and development model for the production base of Gynostemma pentaphyllum (Thunb.) Madino. Sichuan Institute of Chinese Materia Medica, Chongqing, China. Chongging Traditional Chinese Medicine Journal 1994 Jun; 19(6):332-4, 382.<\/p>\n<p>2. Xiao X.H., etc. Agronomic standardization of Gynostemma pentaphyllum (Thunb.) Makino. Sichuan Institute of Chinese Materia Medica, Chongqing, China. Traditional Chinese Medicine Journal of China 1994 May; 19(5):270-2, 318.<br \/>\n5. Specification<\/p>\n<p>PRODUCT NAME JiaogulanExTM<\/p>\n<p>ORIGINAL 01-01-2002<br \/>\nCURRENT UPDATE 01-01-2006<br \/>\n01.00.00 General Information<br \/>\n01.10.00 Source (Botanical Name) Gynostemma pentaphyllum\uff08Thunb.\uff09Makino<br \/>\n01.20.00 Common (Traditional) Name Jiaogulan, penta tea, Amachazuru (Japan), Southern ginseng, Dungkulcha (Korea).<br \/>\n01.30.00 Part Used Full<br \/>\n01.40.00 General Description Light white yellow fine powder<br \/>\n01.50.00 Country of Origin China (PRC)<br \/>\n02.00.00 Analytical Data Value Verification Method<br \/>\n02.20.00 Color Light white yellow fine powder GB 5492-85<br \/>\n02.25.00 Odor Characteristic GB 5492-85<br \/>\n02.30.00 Taste Characteristic GB 5492-85<br \/>\n02.40.30 Gypenosides (by UV) \u226798% ws-z-006-93 (z)<br \/>\n02.45.00 Moisture \u22643.0% AOAC 934.01 15th<br \/>\n02.50.00 Ash \u22645.00% AOAC 942.05,17th<br \/>\n02.70.00 Particle Size \u2267100% (80 mesh) GB 5507-85<br \/>\n02.80.00 Shelf Life 4 years DOH (TAIWAN)\uff1a87041838<br \/>\n03.00.00 Microbiological Data<br \/>\n03.10.00 Standard Plate Count, SPC \u22641000 cfu\/g AOAC 990.12, 16th<br \/>\n03.20.00 Salmonella Negative FDA (BAM) Chapter 5, 8th Ed.<br \/>\n03.25.00 Yeast &amp; Mold \u2264100 cfu\/g FDA (BAM) Chapter 18, 8th Ed.<br \/>\n03.50.00 E. Coli Negative AOAC 975.55, 16th<br \/>\n04.00.00 Heavy Metal<br \/>\n04.10.00 Arsenic \u22641 ppm AOAC 985.01 16th<br \/>\n04.40.00 Lead \u22642 ppm AOAC 985.01, 16th<br \/>\n04.50.00 Mercury \u22640.5 ppm AOAC 971.21\/977.15<br \/>\n04.90.10 Total Heavy Metals \u226410 ppm USP XXII p8 1524, Meth. 1<br \/>\n06.00.00 Nutritional Information Typical Values<br \/>\n06.30.00 Calories (Total) 365 Kcal\/ 100 g Atwater Method, USDA Handbook 74<br \/>\n06.30.10 Calories from Fat 0 Kcal\/ 100 g Atwater Method, USDA Handbook 74<br \/>\n06.35.00 Fat (Total Fat) 0 g\/ 100g AOAC 954.02, 15th<br \/>\n06.45.00 Total Carbohydrates 89.2 g\/ 100g AOAC 979.06<br \/>\n06.50.00 Dietary Fiber 5.9 g\/ 100g AOAC 991.43<br \/>\n06.55.00 Protein (% Nitrogen x 6.25) 2.0 g\/ 100g AOAC 992.15, 15th<br \/>\n06.60.00 Sodium 71.9 mg \/ 100 g AOAC 968.08, 16th<br \/>\n10.00.00 Other Information<br \/>\n10.50.00 Added Ingredients \/ Manufacturing Aids None<br \/>\n10.50.10 Flavors (Natural or Synthetic) Natural (None Added)<br \/>\n10.50.15 Colors (Natural or Synthetic) Natural (None Added)<br \/>\n10.50.20 Sweeteners (IF yes, residue level) Natural (None Added)<br \/>\n10.50.25 Salt (If yes, residue level) Natural (None Added)<br \/>\n10.50.30 Antioxidants \/ Preservatives (If yes, amount) Natural (None Added)<br \/>\n10.50.35 Sulfites or Sulfur added at any stage of production (If yes, residue level) None Added<br \/>\n10.50.40 Solvents None<br \/>\n10.50.45 Treatments (Ethylene Oxide, Propylene Oxide, Irradiation) Details, residue levels Dry Heat<br \/>\n10.50.50 Processing Aids (Silicon Dioxide, Starch, etc.) not already covered None Added<\/p>\n<p>6. Indications, Contraindications, Adverse Effects and Drug Interactions<\/p>\n<p>Indications<\/p>\n<p>Several in vivo and human studies on Jiaogulan were conducted using different type of Jiaogulan products with different concentration of gypenosides in them. Based on our own research and experience, we recommend a daily dosage between 200mg to 350 mg of a standardized Jiaogulan extract with 98% gypenosides in 2 to 3 divided dosages. Do not exceed 350 mg. This is a dosage that is many times smaller than the dosages used in various toxicity studies cited in Section 3.<\/p>\n<p>Contraindications<\/p>\n<p>JiaogulanExTM is safe to take when following the recommended daily dosage. But consult a health care provider prior to using a product containing JiaogulanExTM compounds if you are pregnant, breastfeeding, taking prescription medication(s), or suffer from known liver or kidney disease.<\/p>\n<p>Adverse Effects<\/p>\n<p>No documented adverse effects have been observed or reported in published literatures.<\/p>\n<p>Drug Interactions<\/p>\n<p>No reported drug interactions. But there exist possibilities for interaction with medications so precautions must be taken. It is recommended that consultation with a physician is advised prior to taking JiaogulanExTM.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\nEine Gingseng Alternative aus der chinesischen Volksmedizin<br \/>\nIst jetzt sogar schon als kleine Pflanze im Blumenhandel erh&#228;ltlich, (siehe nachstehende Bezugsquellen) man kann annehmen, dass man in Zukunft noch viel &#252;ber dieses faszinierende Kraut h&#246;ren wird. Anbei finden Sie eine ausf&#252;hrliche Information\u00a0des Lieferanten von Frau Dr. Doris Ehrenberger &#8211; Gesellschaft f. holistische Medizin, der einen qualitativ [&#8230;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[21],"tags":[],"_links":{"self":[{"href":"http:\/\/www.deinayurveda.net\/wordpress\/wp-json\/wp\/v2\/posts\/444"}],"collection":[{"href":"http:\/\/www.deinayurveda.net\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.deinayurveda.net\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.deinayurveda.net\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.deinayurveda.net\/wordpress\/wp-json\/wp\/v2\/comments?post=444"}],"version-history":[{"count":0,"href":"http:\/\/www.deinayurveda.net\/wordpress\/wp-json\/wp\/v2\/posts\/444\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.deinayurveda.net\/wordpress\/wp-json\/wp\/v2\/media?parent=444"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.deinayurveda.net\/wordpress\/wp-json\/wp\/v2\/categories?post=444"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.deinayurveda.net\/wordpress\/wp-json\/wp\/v2\/tags?post=444"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}